Mesenchymal stem cells: biological properties and clinical applications
نویسندگان
چکیده
منابع مشابه
Immunoregulation by Mesenchymal Stem Cells: Biological Aspects and Clinical Applications
Mesenchymal stem cells (MSCs) are multipotent cells capable of differentiation into mesenchymal lineages and that can be isolated from various tissues and easily cultivated in vitro. Currently, MSCs are of considerable interest because of the biological characteristics that confer high potential applicability in the clinical treatment of many diseases. Specifically, because of their high immuno...
متن کاملMesenchymal Stem Cells Isolated from Adipose and Other Tissues: Basic Biological Properties and Clinical Applications
Mesenchymal stem cells (MSCs) are adult stem cells that were initially isolated from bone marrow. However, subsequent research has shown that other adult tissues also contain MSCs. MSCs originate from mesenchyme, which is embryonic tissue derived from the mesoderm. These cells actively proliferate, giving rise to new cells in some tissues, but remain quiescent in others. MSCs are capable of dif...
متن کاملMesenchymal Stem Cells - Sources and Clinical Applications.
SUMMARY: Although mesenchymal stem cells (MSC) from different tissue sources share many characteristics and generally fulfill accepted criteria for MSC (plastic adherence, certain surface marker expression, and ability to differentiate into mesenchymal tissues), we are increasingly learning that they can be distinguished at the level of cytokine production and gene expression profiles. Their ab...
متن کاملMesenchymal stem cells: characteristics and clinical applications.
Mesenchymal stem cells (MSCs) are bone marrow populating cells, different from hematopoietic stem cells, which possess an extensive proliferative potential and ability to differentiate into various cell types, including: osteocytes, adipocytes, chondrocytes, myocytes, cardiomyocytes and neurons. MSCs play a key role in the maintenance of bone marrow homeostasis and regulate the maturation of bo...
متن کاملAn Applied Research in Properties and Clinical Application of Bone Marrow of Mesenchymal Stem Cells
In the last 15 years, there has been a significant increase in the number of researchers interested in studying Mesenchymal Stem Cells (MSCs). MSCs are self-renewing, heterogenic, and multipotent cells that have multi-lineage potential to differentiate not only in to cell types of mesodermal origin but also other various cell lineage MSCs migrate to inflammatory tissues and apply immunosuppress...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Expert Opinion on Biological Therapy
سال: 2010
ISSN: 1471-2598,1744-7682
DOI: 10.1517/14712598.2010.519333